Module 6: Pediatric Trauma Analgesia and Sedation
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Drug |
Dosage |
Effects |
Duration |
Pros |
Cons |
---|
Midazolam (Versed) |
- PO: 0.25-0.5 mg/kg
- PR: 0.25-0.5 mg/kg
- IN: 0.2 mg/kg
- IV: 0.1 mg/kg
|
Anxiolysis, amnesia, sedation/ hypnosis |
45-60 min |
Commonly used for treatment of anxiety and agitation. Multiple routes. Rapid onset. Hemodynamically stable |
Hypoventilation, rare paradoxical reactions |
Dexmedetomidine (Precedex) |
- Buccal: 1-2 MCG/kg
- IN: 1-2 MCG/kg
|
Anxiolysis, sedation |
40-135 min |
Multiple routes. No respiratory depression |
Bradycardia |
Ketamine |
- PO: 5-8 mg/kg
- IM: 4-5 mg/kg
- IV: 1-2 mg/kg
|
Anxiolysis, sedation, analgesia |
3 h (PO) |
Rapid onset. Multiple routes. Hemodynamically stable. No respiratory depression |
Salivation (consider co-administration with glycopyrrolate or atropine), hallucinations |
Clonidine |
PO: 4 MCG/kg |
Anxiolysis |
45-90 min |
Tasteless |
Bradycardia, hypotension |
Module 6: Pediatric Trauma Analgesia and Sedation